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N-Acetyl L-Cysteine (NAC) powder

(66 customer reviews)
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N-Acetyl L-Cysteine (NAC) powder

$39.98 – $89.95

FOCAL NUTRITION®: Proudly Australian Owned and Operated!

100% PURE N-Acetyl L-Cysteine (NAC)

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  • PHARMACEUTICAL GRADE
  • GMP-CERTIFIED MANUFACTURING
  • 300G/300 SERVES OR 1KG/ 1000 SERVES
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Save when you order more! *DISCOUNTS BASED ON TOTAL CART* You can add 1 of everything! Feel free to get in contact with us if you want even larger quantities: info@focalnutrition.com.au
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Description

N-Acetylcysteine (NAC) is a powerful antioxidant and supplement form of the amino acid cysteine. It is widely known for its ability to support liver health, act as a potent antioxidant, and provide numerous other benefits for both physical and mental well-being. NAC works primarily by increasing levels of glutathione, one of the body’s most important antioxidants, which helps combat oxidative stress and supports cellular health.

Here are the key health benefits of NAC:

1. Supports Liver Health and Detoxification

NAC is perhaps best known for its role in supporting liver health and detoxification. It is commonly used in hospitals as an antidote to acetaminophen (Tylenol) overdose, where it helps prevent liver damage by replenishing glutathione levels.

  • Liver Detoxification: NAC helps in the detoxification process by increasing the levels of glutathione in the liver. Glutathione binds to toxins, making them easier for the body to eliminate.
  • Prevents Liver Damage: NAC can help prevent liver damage from toxins, alcohol, and medications, and is often used to support liver function in individuals with liver disease.
  • Chronic Liver Disease: NAC has been shown to improve liver function in conditions like non-alcoholic fatty liver disease (NAFLD) and hepatitis by reducing inflammation and oxidative stress.
2. Powerful Antioxidant and Cellular Protection

As a precursor to glutathione, NAC helps enhance the body’s ability to fight oxidative stress, which is involved in aging and various diseases, including cancer, heart disease, and neurodegenerative conditions.

  • Reduces Oxidative Stress: By increasing glutathione levels, NAC helps neutralize harmful free radicals, reducing oxidative stress that can damage cells and tissues.
  • Supports Immune Function: Glutathione plays a crucial role in maintaining a healthy immune system, helping to fight infections and inflammation. NAC has been shown to improve immune function, especially in individuals with compromised immunity.
3. Promotes Respiratory Health

NAC has been shown to support lung health, especially in individuals with chronic respiratory conditions. It helps thin mucus, making it easier to expel, and can improve lung function.

  • Chronic Respiratory Conditions: NAC is commonly used in conditions like chronic obstructive pulmonary disease (COPD), chronic bronchitis, and asthma. It can help reduce mucus viscosity, improve breathing, and reduce symptoms such as coughing and wheezing.
  • Preventing Respiratory Infections: Some studies suggest NAC can reduce the frequency of respiratory infections, as it boosts the body’s natural defenses and supports lung health.
  • Mucolytic Properties: NAC works as a mucolytic agent, breaking down mucus and reducing its thickness, which helps clear the airways, especially in individuals with conditions like cystic fibrosis.
4. Mental Health Support and Mood Regulation

NAC has been studied for its potential benefits in mental health conditions, particularly due to its antioxidant properties and its ability to regulate certain neurotransmitters.

  • Mood Disorders: NAC has been found to reduce symptoms of depression and anxiety in some individuals, likely due to its ability to balance glutamate (an excitatory neurotransmitter) and increase serotonin and dopamine levels.
  • Addiction and Compulsive Behaviors: NAC has shown promise in treating addictions, particularly cocaine and nicotine dependence, by modulating glutamate signaling in the brain. It may also reduce symptoms of obsessive-compulsive disorder (OCD) and bipolar disorder.
  • Schizophrenia: NAC has been studied as an adjunct therapy in schizophrenia, with some evidence suggesting it may reduce symptoms, including cognitive dysfunction and negative symptoms, by restoring glutathione levels in the brain.
5. Supports Cardiovascular Health

NAC can help improve heart health by reducing oxidative stress, inflammation, and supporting healthy blood flow.

  • Reduces Oxidative Stress: NAC’s antioxidant properties help reduce oxidative damage to blood vessels and the heart, which can contribute to atherosclerosis and other cardiovascular diseases.
  • Lowers Blood Pressure: Some studies suggest that NAC may help reduce blood pressure, particularly in people with hypertension, by improving endothelial function and reducing vascular inflammation.
  • Reduces Homocysteine Levels: Elevated levels of homocysteine, an amino acid, are linked to an increased risk of heart disease. NAC may help lower homocysteine levels, reducing cardiovascular risk.
6. Helps with Immune System Function

NAC is known for its role in boosting immune function, partly through its ability to increase glutathione levels, which is critical for immune cell function.

  • Boosts Glutathione Levels: Glutathione is essential for the optimal functioning of immune cells such as lymphocytes and macrophages, which fight infections. NAC supports the production of glutathione and, in turn, bolsters the immune response.
  • Reduces Inflammation: NAC has anti-inflammatory properties that help lower chronic inflammation in the body, which is linked to numerous diseases, including autoimmune disorders, cardiovascular disease, and diabetes.
7. Supports Healthy Skin and Hair

NAC may also be beneficial for skin and hair health due to its antioxidant properties, ability to combat oxidative stress, and support of collagen synthesis.

  • Skin Health: NAC may help reduce the appearance of wrinkles and improve skin elasticity by supporting the synthesis of collagen, a protein vital for skin integrity. It can also reduce skin damage caused by UV exposure and pollution.
  • Hair Health: NAC’s role in promoting collagen production may also benefit hair health, as collagen is important for healthy hair follicles. Additionally, NAC may help reduce oxidative damage to hair follicles, potentially supporting hair growth.
8. Supports Kidney Health

NAC has potential protective effects for kidney health, particularly in reducing damage from oxidative stress, toxins, and medications.

  • Renal Protection: NAC is sometimes used to prevent kidney damage associated with contrast dye used in imaging tests and certain drugs that can be toxic to the kidneys.
  • Chronic Kidney Disease: Some studies suggest that NAC supplementation may help reduce the progression of chronic kidney disease (CKD) by supporting renal function and reducing oxidative stress.
9. Helps in Weight Loss and Metabolism

Some research suggests that NAC may support weight loss by improving metabolic function and reducing insulin resistance.

  • Improved Insulin Sensitivity: NAC has been shown to improve insulin sensitivity, which helps with better glucose metabolism and may aid in weight management, particularly in individuals with type 2 diabetes or metabolic syndrome.
  • Fat Loss and Metabolism: By supporting liver function and increasing antioxidant capacity, NAC can potentially help improve fat metabolism, which may support weight loss or the maintenance of a healthy weight.
10. Potential Anti-Cancer Effects

While research is still in the early stages, some studies suggest that NAC may have potential anti-cancer properties due to its ability to reduce oxidative stress and improve cellular health.

  • Antioxidant Action: NAC’s ability to boost glutathione levels helps protect cells from oxidative damage, which is a contributing factor to cancer development. NAC may help protect DNA from mutations that could lead to cancer.
  • Chemotherapy Support: NAC may help reduce the side effects of chemotherapy, such as oxidative damage and inflammation, and enhance the overall effectiveness of treatment.

How to Use NAC:

The typical dose of NAC ranges from 600 mg to 1,800 mg per day, depending on the specific health needs. It can be taken in capsules, tablets, or powder form, and is often divided into two or three doses per day.

  • For general health and antioxidant support: 600 mg to 1,200 mg daily.
  • For respiratory conditions: 600 mg to 1,800 mg daily.
  • For liver detoxification or chronic liver conditions: 1,200 mg to 2,400 mg daily.
  • For mental health or addiction support: 600 mg to 2,000 mg daily.

Precautions and Side Effects:

  • Mild Side Effects: NAC is generally well-tolerated, but some people may experience gastrointestinal discomfort, such as nausea, diarrhea, or bloating.
  • Allergic Reactions: Rarely, some individuals may experience allergic reactions such as rash or itching.
  • Interaction with Medications: NAC may interact with certain medications, such as nitroglycerin (which may cause a headache), and medications for blood pressure or diabetes. Always consult with a healthcare provider before starting NAC, particularly if you are on medication or have underlying health conditions.

Conclusion:

N-Acetylcysteine (NAC) is a versatile and highly beneficial supplement with a wide range of health benefits. From supporting liver and respiratory health to promoting cognitive function, boosting the immune system, and improving heart health, NAC offers a variety of advantages. Its antioxidant properties, ability to increase glutathione, and potential role in detoxification make it a valuable supplement for overall health and well-being. As always, it’s important to consult with a healthcare provider before adding NAC to your routine, especially if you have specific health concerns or are taking medications.

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Established in 2016, we’ve been providing wholesale prices and quality products across Australia. We are incredibly passionate about fitness, health and education, with the ultimate goal to improve everyone’s life. Join us on our journey, as we hope to join you on yours!

Additional information

Flavour

Unflavoured
Size

300g (300 serves), 1kg (1000 serves)

FAQs

We recommend consuming 1 gram (~1/3 scoop) of NAC daily at any time of day (Tenorio et al. 2021).

Yes, this product is great for women as well!

1. What does N-acetyl L-cysteine do?

NAC has cell-protective effects which work through antioxidant and anti-inflammatory mechanisms. On the antioxidant side, NAC is a potent upregulator of glutathione levels, one of the main anti-oxidants in the human body (Zhitkovich, 2019 & Oka et al. 2000). Critically, NAC is far superior at increasing glutathione levels as supplementation of glutathione direction results in compound breakdown before it can be used.

Glutathione is found in every cell of the body and is intertwind with every critical process in the body from DNA synthesis to redox balance and healthy cell death (Sies, 1999).

2. Is N-acetyl L-cysteine safe?

Yes, NAC has been extensively studied for over 60 years. No adverse side effects were observed even with excessive doses 20 times higher than the 1g recommendation (Miller & Rumack, 1983). Another clincal trial reported no significant side effects at 8g/ day (Atkuri et al. 2007). However mild gastric distress may result in some individuals at these extremely high doses (Miller & Rumack, 1983 & Atkuri et al. 2007). We strongly recommend sticting to recommended dosage.

3. Should I use NAC or glutathione?

It may make more sense to supplement with glutathione directly to increase glutathione levels. However, the research now shows us that supplementation of glutathione itself is rapidly broken down by the digestive tract before it can be used. NAC is far more effective at crossing across the digestive tract and increases glutathione levels far above glutathione supplementation itself!

SHIPPING IS FREE!

As an added bonus we upgrade all orders to EXPRESS for free when you order over $99 worth of supplements!

We use Australia Post for the vast majority of our deliveries. Although they aren't perfect, in our experience they provide the most consistent service, speed and affordability. From time-to-time we experience delays (especially over holiday periods), please let us know and we will do out best to help assist in getting your products delivered. Please understand that we will do our best to refund or replace lost packages, but we cannot refund in-transit purchases due to slow postage. Sincere apologies for any inconvenience caused.

  1. Atkuri, K. R., Mantovani, J. J., Herzenberg, L. A., & Herzenberg, L. A. (2007). N-Acetylcysteine--a safe antidote for cysteine/glutathione deficiency. Curr Opin Pharmacol, 7(4), 355-359.
  2. Birnbaum, S. M., Winitz, M., & Greenstein, J. P. (1957). Quantitative nutritional studies with water-soluble, chemically defined diets. III. Individual amino acids as sources of non-essential nitrogen. Arch Biochem Biophys, 72(2), 428-436.
  3. Gazit, V., Ben-Abraham, R., Pick, C. G., Ben-Shlomo, I., & Katz, Y. (2003). Long-term neurobehavioral and histological damage in brain of mice induced by L-cysteine. Pharmacol Biochem Behav, 75(4), 795-799.
  4. Miller, L. F., & Rumack, B. H. (1983). Clinical safety of high oral doses of acetylcysteine. Semin Oncol, 10(1 Suppl 1), 76-85.Schwalfenberg, G. K. (2021). N-Acetylcysteine: A Review of Clinical Usefulness (an Old Drug with New Tricks). J Nutr Metab, 2021, 9949453.
  5. Oka, S.-i., Kamata, H., Kamata, K., Yagisawa, H., & Hirata, H. (2000). N-Acetylcysteine suppresses TNF-induced NF-κB activation through inhibition of IκB kinases. FEBS Letters, 472(2), 196-202.
  6. Sheffner, A. L. (1963). The Reduction In Vitro In Viscosity of Mucoprotein Solutions by a New Mucolytic Agent, N-acetyl-L-Cysteine. Ann N Y Acad Sci, 106(2), 298-310.
  7. Sies, H. (1999). Glutathione and its role in cellular functions. Free Radic Biol Med, 27(9-10), 916-921.
  8. Tenório, M., Graciliano, N. G., Moura, F. A., Oliveira, A. C. M., & Goulart, M. O. F. (2021). N-Acetylcysteine (NAC): Impacts on Human Health. Antioxidants (Basel), 10(6).
  9. Zhitkovich, A. (2019). N-Acetylcysteine: Antioxidant, Aldehyde Scavenger, and More. Chemical research in toxicology, 32(7), 1318-1319.

66 reviews for N-Acetyl L-Cysteine (NAC) powder

5.0
Based on 66 reviews
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1-50 of 66 reviews
  1. C
    catattackanneb(eBay)
    Reviewer

    Won’t know until I have used it for a month or so

  2. J
    johnnysully2001(eBay)
    Reviewer

    Well priced, good quality.

  3. G
    grant1975grant(eBay)
    Reviewer

    Very quick postage… Thank you very much

  4. X
    xetrov87(eBay)
    Reviewer

    Top product and service

  5. H
    happyjadehorse(eBay)
    Reviewer

    Thx

  6. F
    frewerfrewer(eBay)
    Reviewer

    This NAC doesn’t give mea headache, I like it.Ta

  7. J
    joadaw87(eBay)
    Reviewer

    The item was exactly what I ordered and it came quickly

  8. J
    jouncer(eBay)
    Reviewer

    thanks

  9. M
    mistyfour(eBay)
    Reviewer

    Thanks

  10. L
    l0luke0l(eBay)
    Reviewer

    Thank you for fast post and a great price A +++

  11. C
    countryoforigin(eBay)
    Reviewer

    Supafast postage! 2nd time purchasing……5 star seller🌟..will keep as favourite seller~many thanks..Love💓..

  12. S
    stelios333777333(eBay)
    Reviewer

    Speedy delivery, fantastic

  13. DR
    dags.r(eBay)
    Reviewer

    Smooth, easy transaction with fast postage. Thanks!

  14. 5
    55pmh(eBay)
    Reviewer

    Received with thanks, quick postage.

  15. O
    original_deepthought(eBay)
    Reviewer

    Quick to Post – Exactly as described – Definately one of my favourite sellers for this type of product. Cheers!

  16. F
    flexmaster001(eBay)
    Reviewer

    Quick delivery. Good product

  17. S
    shane88008(eBay)
    Reviewer

    PURE NAC N-Acetyl L-Cysteine – AS GOOD AS ANY SIMILAR PRODUCT ON THE MARKET!

  18. G
    gr33nb33ns(eBay)
    Reviewer

    Prompt shipping, excellent product, will be back, thanks 🙏

  19. W
    wwwbear(eBay)
    Reviewer

    Perfectly as described

  20. M
    maffew45(eBay)
    Reviewer

    Ordered from this seller numerous times and always quality products I absolutely recommend.

  21. H
    hmistu(eBay)
    Reviewer

    on time

  22. A
    astero59(eBay)
    Reviewer

    Not first time order. Great supplement.

  23. T
    traybits(eBay)
    Reviewer

    Nice

  24. R
    relmasri(eBay)
    Reviewer

    NAC coupled with glycine is excellent for sleep.

  25. AA
    au2015.ank(eBay)
    Reviewer

    Love this product, helped me and my family through flue, COVID and coughing. Fast recovery to be expected everytime

  26. O
    ozymandias793(eBay)
    Reviewer

    Its NAC. Smells and tastes foul. Good way to know its genuine. More crystalline than I’m used to, but should mix ok. Good value and the desiccant pack is a good idea. Measuring spoon included too.

  27. E
    exorsys(eBay)
    Reviewer

    Item was well packaged and exactly what I expected.

  28. B
    bst_fnk_97cjqm1qz(eBay)
    Reviewer

    Item as described. Prompt shipping. Excellent Seller.

  29. P
    paulini173(eBay)
    Reviewer

    I haven’t tried the product yet, but was very happy with the service, price & communication of the seller. I recommend them highly!! 🙂

  30. N
    nugzta(eBay)
    Reviewer

    I believe it’s the best price in Australia if you’re looking for NAC. Highly recommend the seller!

  31. R
    relmasri(eBay)
    Reviewer

    Great with glycine for sleep.

  32. A
    a**57(eBay)
    Reviewer

    Great thank you! 🙂

  33. B
    bluetriangle4(eBay)
    Reviewer

    Great service! Thanks+++

  34. L
    liquid_8_sales(eBay)
    Reviewer

    Great service, quick delivery, great product

  35. C
    clix-64(eBay)
    Reviewer

    Great seller

  36. N
    niki2024(eBay)
    Reviewer

    Great quality!

  37. B4
    brig.40cal(eBay)
    Reviewer

    Great product, as described with good communication and fast delivery. Good seller👍🏼

  38. A
    absolutedive(eBay)
    Reviewer

    Great product well packaged and fast delivery as well as excellent Customer follow-up. Highly recommended seller. 

  39. D
    dann12309(eBay)
    Reviewer

    Great product as described. Quick delivery.

  40. E
    ethan3690(eBay)
    Reviewer

    Great product

  41. F2
    fdc.2009(eBay)
    Reviewer

    Great price, fast delivery time, great communication, product well-packed, item as described, very pleased with transaction.

  42. T
    thecharliec(eBay)
    Reviewer

    Great item, smooth sale. A++++

  43. V
    velsta(eBay)
    Reviewer

    Great Ebay’er

  44. J
    josipara(eBay)
    Reviewer

    Goods received Thanks

  45. K
    kennyishii(eBay)
    Reviewer

    Good Thanks

  46. JD
    john.duggan(eBay)
    Reviewer

    Good quality product, prompt delivery,

  47. Y
    yourmediavoice(eBay)
    Reviewer

    Good products

  48. R
    rookielikeslearning(eBay)
    Reviewer

    Good item, Easy transaction. Thank you. A+

  49. B
    benhoff99(eBay)
    Reviewer

    good communications

  50. A
    aus_spook(eBay)
    Reviewer

    Fast shipping, great prices too. Excellent experience, thank you!

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